Besides the federal payroll and unemployment taxes you will owe, each State also assesses their own unemployment taxes. Because governments hate simplicity, each State has a different tax rate and wage cap. Not only does the tax rate vary by State, but also by how long you have been an employer. Because each household's situation is different, there is no way maintain a system that can tell you your exact State unemployment tax liability. You will need to contact your State's Unemployment Agency Office. Links are provided below. If you would prefer to call, you can find a list of unemployment office phone numbers here.
State unemployment taxes are payable every quarter. There is a definate benefit to paying on time. By doing so, you earn a reduction of your federal unemployment tax (FUTA) rate from 6.2% down to 0.6*% (on wages up to $7,000), potentially saving you up to $378.
* Residents of some States will get less of a FUTA reduction because these states borrowed money from the federal government to pay for unemployment benefits and have not paid Washington back yet. Currently Indiana, Michigan, and South Carolina are on the delinquent list, but more states will be added in 2012. See the links below to your State's office for specifics.